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Inhibition of constitutively activated Stat3 correlates with altered Bcl-2/Bax expression and induction of apoptosis in mycosis fungoides tumor cells

✍ Scribed by Nielsen, M; Kæstel, CG; Eriksen, KW; Woetmann, A; Stokkedal, T; Kaltoft, K; Geisler, C; Röpke, C; Ødum, N

Book ID
110054207
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
183 KB
Volume
13
Category
Article
ISSN
0887-6924

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We have studied the expression of the apoptosis-regulating genes bcl-2, bcl-x, box and APO-I /fas (CD95) in human breast cancer. The expression pattern of these genes in human breast-cancer tissues and breast-cancer-derived cell lines was compared to that seen in normal breast epithelium and breast