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Inhibition of colchicine absorption by the fat substitutes, sucrose polyester and tricarballylate triester, in the rat

✍ Scribed by Kamel Benmoussa; Jean-Michel Schermann; Jean-Marie Bourre


Book ID
118347057
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
496 KB
Volume
56
Category
Article
ISSN
0024-3205

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## Abstract Colchicine inhibited the initiation of DNA synthesis by hepatocytes in vivo and by WI‐38 and C3H10T 1/2 cells in vitro. All three cell types were most sensitive to colchicine when it was administered at the time of, or shortly after, proliferative activation (by partial hepatectomy or m