Inhibition of clinical and environmental Cryptococcus neoformans isolates by two Brazilian killer yeasts
✍ Scribed by Alexandre M. Fuentefria; Inélia M. Franskoviaki; Luisa W. Mercado; Jesus P. Ramos; Marilene H. Vainstein; Patrícia Valente
- Book ID
- 102389753
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 206 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0233-111X
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✦ Synopsis
Two killer yeast strains (HB55 and HB88) capable of inhibiting human pathogenic fungi were isolated from leaves of Hibiscus rosa-sinensis in Brazil. These isolates were identified by conventional methods and sequencing of the D1/D2 region of the 26S rDNA as Kodamaea ohmeri. They inhibited all Cryptococcus neoformans (vars. neoformans, grubii and gattii) strains tested, including reference, clinical and environmental isolates. The killer phenotype was not cured by thermal treatment.
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In Brazil, 4.5% of the AIDS-related opportunistic infections are caused by Cryptococcus neoformans. This pathogen is a ubiquitous environmental basidiomycetous encapsulated yeast, commonly found in soil and avian excreta. The present study investigates further the population structure of clinical an