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Inhibition of chymotrypsin by alkyl phosphonates: A quantitative structure-activity analysis

✍ Scribed by Carlo Silipo; Corwin Hansch; Ciro Grieco; Antonio Vittoria


Book ID
115704246
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
487 KB
Volume
194
Category
Article
ISSN
0003-9861

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✍ David F. V. Lewis; Craig Sams; George D. Loizou 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 84 KB

## Abstract The results of quantitative structure–activity relationships for eight alkyl benzenes undergoing oxidative metabolism via human CYP2E1 are reported. Molecular orbital calculations via the AM1 method were employed for the generation of electronic structural descriptors against experiment