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Inhibition of chondrocyte apoptosis in vivo following acute osteochondral injury

✍ Scribed by J.G Costouros; A.C Dang; H.T Kim

Book ID
114348611
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
235 KB
Volume
11
Category
Article
ISSN
1063-4584

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## Abstract The objective of the present study was to directly compare levels of chondrocyte apoptosis produced by osteochondral injury in vivo and in vitro. Adult New Zealand White rabbits underwent 2 mm osteochondral drilling of the medial and lateral femoral condyles of a single hind limb. Anima

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## Abstract Chondrocyte apoptosis can be an important contributor to cartilage degeneration, thereby making it a potential therapeutic target in articular diseases. To search for new approaches to limit chondrocytic cell death, we investigated the requirement of polyamines for apoptosis favored by