Inhibition of choline transport in erythrocytes by n-alkanols
✍ Scribed by Rosa Devés; Richard M. Krupka
- Book ID
- 115729424
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 860 KB
- Volume
- 1030
- Category
- Article
- ISSN
- 0005-2736
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## Abstract The inhibition of glucose transport by the non‐ionizable local‐anesthetic benzylalcohol is of the mixed type and independent of pH. The affinity of benzylalcohol to the free carrier is about three times larger than that to the carrier‐glucose complex.
The human erythrocyte membrane carriers for hexoses and nucleosides have several structural features in common. In order to assess functional similarities, the effects of adenosine derivatives on hexose transport and cytochalasin B binding sites were studied. Adenosine inhibited zero-trans uptake of