✦ LIBER ✦

Inhibition of checkpoint kinase 1 abrogates G2/M checkpoint activation and promotes apoptosis under heat stress

✍ Scribed by Yukihiro Furusawa; Takashi Iizumi; Yoshisada Fujiwara; Qing-Li Zhao; Yoshiaki Tabuchi; Takaharu Nomura; Takashi Kondo

Book ID: 106350079
Publisher: Springer
Year: 2011
Tongue: English
Weight: 754 KB
Volume: 17
Category: Article
ISSN: 1360-8185
DOI: 10.1007/s10495-011-0660-7

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

p38 MAP kinase plays a role in G2 checkp

p38 MAP kinase plays a role in G2 checkpoint activation and inhibits apoptosis of human B cell lymphoma cells treated with etoposide

✍ T. Kurosu; Y. Takahashi; T. Fukuda; T. Koyama; T. Miki; O. Miura 📂 Article 📅 2005 🏛 Springer 🌐 English ⚖ 694 KB

Checkpoint kinase 1-mediated phosphoryla

Checkpoint kinase 1-mediated phosphorylation of Cdc25C and bad proteins are involved in antitumor effects of loratadine-induced G2/M phase cell-cycle arrest and apoptosis

✍ Jinn-Shiun Chen; Shyr-Yi Lin; Wei-Ling Tso; Geng-Chang Yeh; Wen-Sen Lee; How Tse 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 678 KB

## Abstract In this study, we first demonstrated that loratadine (LOR), a promising world widely used oral anti‐histamine, effectively inhibits growth of tumors derived from human colon cancer cells (COLO 205) in an in vivo setting. In vitro study demonstrated that the anti‐tumor effects of LOR in