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Inhibition of cellular cholesterol esterification can decrease low density lipoprotein receptor number in human fibroblasts

โœ Scribed by Bruce Middleton


Book ID
115760768
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
387 KB
Volume
145
Category
Article
ISSN
0006-291X

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Inhibition of the binding of low-density
โœ Brown, Michael S. ;Deuel, Thomas F. ;Basu, Sandip K. ;Goldstein, Joseph L. ๐Ÿ“‚ Article ๐Ÿ“… 1978 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 701 KB

A group of proteins and polyarnino acids with positively charged domains were shown to inhibit the binding of 1251-LDL t o its receptor on the surface of human fibroblasts. The list of inhibitory proteins included platelet factor 4 (which has a cluster of lysine residues at its carboxyl terminus), t