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Inhibition of cell division in mammalian cell cultures by hypertonic medium

โœ Scribed by D. N. Wheatley; B. Angus


Book ID
112652979
Publisher
Springer
Year
1973
Tongue
English
Weight
540 KB
Volume
29
Category
Article
ISSN
1420-682X

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The cells of an established mouse fibroblast line, 3T3, have a high plating efficiency and grow rapidly in sparse culture, but stop growing at a very low saturation density in comparison with other lines, because 3T3 is extremely sensitive to contact inhibition of cell division. After each medium ch