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Inhibition of CED-3 zymogen activation and apoptosis in Caenorhabditis elegans by caspase homolog CSP-3

✍ Scribed by Geng, Xin; Shi, Yong; Nakagawa, Akihisa; Yoshina, Sawako; Mitani, Shohei; Shi, Yigong; Xue, Ding

Book ID
109965594
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
734 KB
Volume
15
Category
Article
ISSN
1545-9993

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## Abstract Increased expression of plasminogen activator inhibitor type 1 (PAI‐1) is associated with decreased apoptosis of neoplastic cells. We sought to determine whether PAI‐1 alters apoptosis in vascular smooth muscle cells (VSMC) and, if so, by what mechanisms. A twofold increase in the expre