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Inhibition of cardiac creatine phosphokinase by fluorodinitrobenzene

โœ Scribed by William C.T. Yang; Michael Dubick


Book ID
118937766
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
250 KB
Volume
21
Category
Article
ISSN
0024-3205

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Beta amyloid peptides (AP), etiologically associated with Alzheimer's disease (AD), have been shown to inhibit both glutamine synthetase (GS) and creatine phosphokinase (CPK) in vitro. These two enzymes are affected in AD and are sensitive to oxidative stress. Residue 35 of the AP25-35, the most pot