Inhibition of calcium overload by intrapericardial nitroglycerin as a major mechanism for its potent antifibrillatory effect

Increased endothelial uptake of paclitax

Increased endothelial uptake of paclitaxel as a potential mechanism for its antiangiogenic effects: Potentiation by Cox-2 inhibition

✍ Jaime R. Merchan; Deepa R. Jayaram; Jeffrey G. Supko; Xiaoying He; Glenn J. Bubl 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 354 KB

## Abstract Paclitaxel has antiangiogenic properties, but the mechanisms for the enhanced sensitivity of endothelial cells (ECs) to this drug are not established. The aims of our study were to compare the distribution of paclitaxel into ECs with other cell types, to assess the effects of low doses