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Inhibition of Ca2+ current in ileal cells by cyclopiazonic acid and ryanodine

✍ Scribed by Hristo S. Gagov; Dessislava B. Duridanova; Kiril K. Boev


Book ID
115888338
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
468 KB
Volume
243
Category
Article
ISSN
0014-2999

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Using the whole-cell variation of the patch-clamp technique, we have demonstrated that retinoic acid (RA) blocks Ca channels and inhibits cell proliferation in a mouse hybridoma cell line (MHY206) derived from a fusion of murine myeloma and splenic B cells. In 25 mM external Ca, and with an Na inter