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Inhibition of c-Met activation sensitizes osteosarcoma cells to cisplatin via suppression of the PI3K–Akt signaling

✍ Scribed by Kelai Wang; Yan Zhuang; Chunlan Liu; Yang Li

Book ID: 116179057
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 718 KB
Volume: 526
Category: Article
ISSN: 0003-9861
DOI: 10.1016/j.abb.2012.07.003

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## Abstract Angiogenesis plays a crucial role in tumor growth and metastases. The extent of angiogenesis correlates with the increased invasion and metastasis in a variety of human neoplasms. Vascular endothelial cell proliferation and migration are critical steps in angiogenesis and are regulated