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Inhibition of brain monoamine oxidase-B by Ro19-6327 — in vivo measurerment using positron emission tomography

✍ Scribed by G.W. Price; C.J. Beach; J.C. Cremer; S.K. Luthra; D.R. Turton; A.A. Lammertsma; R. Kettler; M. DaPrada; N. Wood; V. Jamieson; G. McClelland; R.S.J. Frackowiak


Book ID
115884829
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
136 KB
Volume
183
Category
Article
ISSN
0014-2999

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Eight normal subjects (3 females and 5 males) were studied using intravenous L-[11C] deprenyl and positron emission tomography. In a single blind study one subject received tracer alone, one subject received an oral pre-dose of 20 mg of L-deprenyl and 6 subjects received oral pre-doses of 10 to 50 m