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Inhibition of brain acetylcholine biosynthesis by methyldopa in spontaneously hypertensive rats

✍ Scribed by Buccafusco, Jerry J.


Book ID
123155554
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
759 KB
Volume
13
Category
Article
ISSN
0361-9230

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Recent studies in this laboratory have demonstrated that clonidine, a centrally acting antihypertensive drug, can inhibit the function of central cholinergic neurons. We have also provided evidence for enhanced brain cholinergic activity in the spontaneously hypertensive rat (SHR). The purpose of th