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Inhibition of bladder cancer invasion by Sp1-mediated BTG2 expression via inhibition of DNA methyltransferase 1

✍ Scribed by Devanand, Preethi; Kim, Sun Il; Choi, Yong Won; Sheen, Seung Soo; Yim, Hyunee; Ryu, Min Sook; Kim, Se Joong; Kim, Wun-Jae; Lim, In Kyoung

Book ID
126663113
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
917 KB
Volume
281
Category
Article
ISSN
1432-1327

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p16 inhibits matrix metalloproteinase-2
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✍ Chie-Hong Wang; Hui-Chiu Chang; Wen-Chun Hung πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 243 KB

## Abstract Previous studies demonstrate that p16, a cyclin‐dependent kinase inhibitor and a tumor suppressor, may inhibit matrix metalloproteinase‐2 (MMP‐2) expression in human cancer cells to suppress tumor invasion and metastasis. However, the detailed mechanism is still unclear. Our results sho