Inhibition of Biochemical Reactions by Silicon Nanowires through Modulating Enzyme Activities

Melatonin inhibits the growth of DMBA-in

Melatonin inhibits the growth of DMBA-induced mammary tumors by decreasing the local biosynthesis of estrogens through the modulation of aromatase activity

✍ Samuel Cos; Alicia González; Andrés Güezmes; Maria Dolores Mediavilla; Carlos Ma 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 126 KB

Melatonin inhibits the growth of breast cancer cells by interacting with estrogen-responsive pathways, thus behaving as an antiestrogenic hormone. Recently, we described that melatonin reduces aromatase expression and activity in MCF-7 human breast cancer cells, thus modulating the local estrogen bi