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Inhibition of binding of lactoferrin to the human promonocyte cell line THP-1 by heparin: the role of cell surface sulphated molecules

✍ Scribed by Anca Roşeanu; Flori Chelu; Mihaela Trif; Cecilia Motaş; Jeremy H. Brock

Book ID
117480627
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
201 KB
Volume
1475
Category
Article
ISSN
0304-4165

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A group of proteins and polyarnino acids with positively charged domains were shown to inhibit the binding of 1251-LDL t o its receptor on the surface of human fibroblasts. The list of inhibitory proteins included platelet factor 4 (which has a cluster of lysine residues at its carboxyl terminus), t