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Inhibition of biliary glutathione secretion by cyclosporine A in the rat: possible mechanisms and role in the cholestasis induced by the drug

✍ Scribed by Dominica Morán; José M. González De Buitrago; Emilio Fernández; Ana I. Galán; M. Eugenia Muñoz; Rafael Jiménez


Book ID
118567953
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
157 KB
Volume
29
Category
Article
ISSN
0168-8278

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In an attempt to understand the hepatotoxicity associated with immunosuppressive therapy with cy- cloeporin A, we inveatigated the effects of acute cyclosporin A admidstration on biliary secretion, serum bile acid and bilirubin levels and the hietological changes in the hepatic parenchyma in anemthe