The role of adenosine 3′, 5′-cyclic mono
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David R. Wade; Mary E. Burkart
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Article
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1978
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John Wiley and Sons
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English
⚖ 927 KB
## Abstract Incubation of cultured B‐16 melanoma cells with 1‐methyl‐3‐isobutyl xanthine (MIX) produced a sustained rise in intracellular adenosine 3′,5′‐cyclic monophosphate (cAMP) which preceded an increase in the specific activity of tyrosinase (EC 1.10.3.1). Cultures of two clones of melanoma c