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Inhibition of B16 Mouse Melanoma Cell Growth and Induction of Apoptotic Cell Death with 8-Chloroadenosine-3′,5′-monophosphate and Tiazofurin

✍ Scribed by LELA B. KORIĆANAC; DANIJELA V. TODOROVIĆ; NATAŠA M. POPOVIĆ; MIROSLAV A. DEMAJO; SABERA D. RUŽDIJIĆ; ALEKSANDRA M. RISTI-FIRA


Book ID
111478960
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
116 KB
Volume
1030
Category
Article
ISSN
0890-6564

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## Abstract Incubation of cultured B‐16 melanoma cells with 1‐methyl‐3‐isobutyl xanthine (MIX) produced a sustained rise in intracellular adenosine 3′,5′‐cyclic monophosphate (cAMP) which preceded an increase in the specific activity of tyrosinase (EC 1.10.3.1). Cultures of two clones of melanoma c