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Inhibition of avian myeloblastosis virus deoxyribonucleic acid polymerase by synthetic polynucleotides

โœ Scribed by Erickson, Robert J.; Grosch, Josephine C.


Book ID
125953411
Publisher
American Chemical Society
Year
1974
Tongue
English
Weight
835 KB
Volume
13
Category
Article
ISSN
0006-2960

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Nalidixic acid, a very specific inhibitor of bacterial DNA synthesis, has been studied for its action on the avian myeloblastosis virus reverse transcriptase activity. The drug inhibited the DNA synthesis reaction catalyzed by the viral enzyme in the presence of different template-primers. The inhib