✦ LIBER ✦

Inhibition of Autophagy as a Strategy to Augment Radiosensitization by the Dual PI3K/mTOR Inhibitor NVP-BEZ235

✍ Scribed by Maity, A.; Cerniglia, G.J.; Karar, J.; Koumenis, C.

Book ID: 122980552
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 54 KB
Volume: 84
Category: Article
ISSN: 0360-3016
DOI: 10.1016/j.ijrobp.2012.07.130

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Radiosensitization by the Dual PI3K/mTOR

Radiosensitization by the Dual PI3K/mTOR Inhibitor NVP-BEZ235

✍ A. Maity; G.J. Cerniglia; J. Karar 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 50 KB

Inhibition of DNA Double-Strand Break Re

Inhibition of DNA Double-Strand Break Repair by the Dual PI3K/mTOR Inhibitor NVP-BEZ235 as a Strategy for Radiosensitization of Glioblastoma

✍ Gil del Alcazar, C. R.; Hardebeck, M. C.; Mukherjee, B.; Tomimatsu, N.; Gao, X.; 📂 Article 📅 2013 🏛 American Association for Cancer Research 🌐 English ⚖ 446 KB

NVP-BEZ235, a Dual PI3K/mTOR Inhibitor,

NVP-BEZ235, a Dual PI3K/mTOR Inhibitor, Prevents PI3K Signaling and Inhibits the Growth of Cancer Cells with Activating PI3K Mutations

✍ Serra, V.; Markman, B.; Scaltriti, M.; Eichhorn, P. J.A.; Valero, V.; Guzman, M. 📂 Article 📅 2008 🏛 American Association for Cancer Research 🌐 English ⚖ 682 KB

Radiosensitization of prostate cancer ce

Radiosensitization of prostate cancer cells by the dual PI3K/mTOR inhibitor BEZ235 under normoxic and hypoxic conditions

✍ Potiron, Vincent A.; Abderrhamani, Rym; Giang, Eric; Chiavassa, Sophie; Di Tomas 📂 Article 📅 2013 🏛 Elsevier Science 🌐 English ⚖ 767 KB

The efficacy of a novel, dual PI3K/mTOR

The efficacy of a novel, dual PI3K/mTOR inhibitor NVP-BEZ235 to enhance chemotherapy and antiangiogenic response in pancreatic cancer

✍ Niranjan Awasthi; Peter L. Yen; Margaret A. Schwarz; Roderich E. Schwarz 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 419 KB

## Abstract Gemcitabine has limited clinical benefits for pancreatic ductal adenocarcinoma (PDAC). The phosphatidylinositol‐3‐kinase (PI3K)/AKT and mammalian target of rapamycin (mTOR) signaling pathways are frequently dysregulated in PDAC. We investigated the effects of NVP‐BEZ235, a novel dual PI

203 The Dual PI3K/mTOR Inhibitor NVP-BEZ

203 The Dual PI3K/mTOR Inhibitor NVP-BEZ235 Prevents Hypoxia-induced Epithelial to Mesenchymal Transition Through Interfering the Expression of Hif-1alpha

✍ Zhang, L.; Cao, J.; Lin, G.Y.; Hu, Y.Z.; Yang, B.; He, Q.J. 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 62 KB