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Inhibition of Apomorphine-induced Hypermotility in Rats by Chlorpromazinc, Perphenazine, Thioridazine and Melperone

✍ Scribed by Lassen, Jørgen Buus

Book ID
114799418
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
571 KB
Volume
40
Category
Article
ISSN
0001-6683

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Inhibition of 4,α-dimethyl-m-tyramine (H 77/77)-induced hypermotil ity in rats by single and repeated administration of chlorpromazine, haloperidol, clozapine and thioridazine
✍ J. Buus Lassen 📂 Article 📅 1975 🏛 Springer 🌐 English ⚖ 486 KB

The effect of H 77/77 (5 mg/kg s.c.) on motility of rats kept in a familiar cage was investigated. H 77/77 produced hypermotility, which was reduced by oral pretreatment with chlorpromazine, haloperidol, clozapine and thioridazine. The 4 neuroleptics were administered acutely and for a 14 day period