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Inhibition of antigen-presenting cell function by alendronate in vitro

✍ Scribed by Paolo Sansoni; Giovanni Passeri; Francesco Fagnoni; Nahid Mohagheghpour; Gianluca Snelli; Vincenzo Brianti; Dr. Edgar G. Engleman


Book ID
112119559
Publisher
American Society for Bone and Mineral Research
Year
2009
Tongue
English
Weight
754 KB
Volume
10
Category
Article
ISSN
0884-0431

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Exposure to haptens initiates a series of immune and inflammatory reactions that cause migration of epidermal Langerhans cells (LC) to draining lymph nodes, antigen processing, and presentation to T cells. In the present study, the antigen-presenting cell (APC) function of epidermal cells (EC) follo