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Inhibition of antigen-induced dyspnea in rats by FPL 55712 and lipoxidase inhibitors

✍ Scribed by H. Piechuta; G. Holme


Book ID
107927383
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
82 KB
Volume
4
Category
Article
ISSN
0192-0561

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Inhibition of Antigen-induced Pulmonary
✍ R.E. Howell; L.P. Jenkins; L.E. Fielding; D. Grimes πŸ“‚ Article πŸ“… 1995 πŸ› Elsevier 🌐 English βš– 446 KB

SUMMARY: Rolipram, a phosphodiesterase type 4 (PDE4)-selective inhibitor, has been demonstrated to inhibit antigen-induced pulmonary eosinophilia in guinea pigs and monkeys, suggesting that PDE4-selective inhibitors could be useful for treating asthma. Although the rat is used extensively in preclin