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Inhibition of an Innate Antiviral Response by Human Cytomegalovirus UL97 Kinase is Antagonized by Maribavir

✍ Scribed by Mark Prichard; Shannon Daily; Amie Perry; Caroll Hartline; Earl Kern

Book ID: 113457454
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 67 KB
Volume: 74
Category: Article
ISSN: 0166-3542
DOI: 10.1016/j.antiviral.2007.01.043

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Function of human cytomegalovirus UL97 k

Function of human cytomegalovirus UL97 kinase in viral infection and its inhibition by maribavir

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## Abstract The serine/threonine kinase expressed by human cytomegalovirus from gene UL97 phosphorylates the antiviral drug ganciclovir, but its biological function is the phosphorylation of its natural viral and cellular protein substrates which affect viral replication at many levels. The UL97 ki