✦ LIBER ✦
Inhibition of an endogenous growth-related proteinase enhances the recovery of a negative growth regulator from cultured human cells.
✍ Scribed by Sushila Manilal; G.Kenneth Scott; Cynthia A. Tse
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 337 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1065-6995
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✦ Synopsis
Abstract
The possibility that a growth‐related proteinase may act by degrading a negative growth regulatory protein has been investigated. Proteinase inhibitors which inhibit the enzyme also enhance the accumulation of the growth regulator by human fibroblasts. The negative growth regulator shows a similar specificity of inhibition of cellular growth to inhibitors of the growth‐related proteinase.