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Inhibition of AKT Pathway Augments Combination Therapy

โœ Scribed by Scott Magnuson; Eben Rosenthal

Book ID
116815689
Publisher
SAGE Publications
Year
2010
Tongue
English
Weight
42 KB
Volume
143
Category
Article
ISSN
0194-5998

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## Abstract Prostate cancer cells are generally dependent on androgen stimulation mediated by the androgen receptor (AR) for growth and survival, and, therefore, hormonal manipulation, such as castration and/or the use of AR antagonists, results in a regression of the cancer. However, this treatmen