Inhibition of aggression by progesterone and its metabolites in female Syrian hamsters

Involvement of genotoxic effects in the

Involvement of genotoxic effects in the initiation of estrogen-induced cellular transformation: Studies using Syrian hamster embryo cells treated with 17β-estradiol and eight of its metabolites

✍ Takeki Tsutsui; Yukiko Tamura; Eiichi Yagi; J. Carl Barrett 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 114 KB 👁 1 views

To examine a direct involvement of genotoxic effects of estrogens in the initiation of hormonal carcinogenesis, the abilities of 17beta-estradiol (E2) and 8 of its metabolites to induce cellular transformation and genetic effects were studied using the Syrian hamster embryo (SHE) cell model. Treatme