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Inhibition of Adenosine Diphosphate-induced Platelet Aggregation by Histamine

✍ Scribed by CONSTANTINE, JAY W.

Book ID: 109644350
Publisher: Nature Publishing Group
Year: 1965
Tongue: English
Weight: 119 KB
Volume: 207
Category: Article
ISSN: 0028-0836
DOI: 10.1038/207091a0

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## Abstract A sensitive in vitro technique was used to demonstrate the inhibitory effects of histamine on human blood platelets. Platelet aggregation by epinephrine was completely inhibited at 10^−3^ M concentrations of histamine. Persistent elevations of cyclic AMP levels were shown to occur in th