Inhibition of adenosine deaminase activity reveals an intense active transport of adenosine into neurons in primary cultures

Postsynaptic inhibition by adenosine in

Postsynaptic inhibition by adenosine in hippocampal CA3 neurons: Co2+-sensitive activation of an inwardly rectifying K+conductance

✍ C. Alzheimer; G. Bruggencate 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 945 KB

The properties of the current underlying the membrane hyperpolarization evoked by adenosine (50-100 microM) were investigated in hippocampal CA3 neurons in vitro using current-clamp and single-electrode voltage-clamp techniques. In voltage-clamp measurements, the adenosine-induced current (IAdo) was