Inhibition of acetylcholinesterase by chelates III
โ Scribed by Ernest Mario; Sanford Bolton
- Publisher
- John Wiley and Sons
- Year
- 1968
- Tongue
- English
- Weight
- 535 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
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It is shown that the influence of alkylammonium salts on the acetylcholinesterase-catalyzed hydrolysis of cationic substrates is caused by two factors: (A) nonspecific binding (condensation) of inhibitory cations on the polyanionic enzyme molecule due to electrostatic interactions, and (B) binding o