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Inhibition of 50S Ribosomal Subunit Assembly inHaemophilus influenzaeCells by Azithromycin and Erythromycin

โœ Scribed by W. Scott Champney; Mindy Miller

Publisher
Springer
Year
2002
Tongue
English
Weight
152 KB
Volume
44
Category
Article
ISSN
0343-8651

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โœ Saltzman, Larry ;Apirion, David ๐Ÿ“‚ Article ๐Ÿ“… 1976 ๐Ÿ› Springer ๐ŸŒ English โš– 644 KB

Expression of resistance to erythromycin in Escherichia coli, caused by an altered L4 protein in the 50S ribosomal subunit, can be masked when two additional ribosomal mutations affecting the 30S proteins S5 and S12 are introduced into the strain (Saltzman, Brown, and Apriion, 1974). Ribosomes from