Naftopidil inhibits 5-hydroxytryptamine-
β
R. Kirsten; M. Breidert; K. Nelson; A. Heine; S. Rosenkranz; B. Erdeg; G. Niebch
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Article
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1994
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Springer
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English
β 405 KB
Naftopidil exerts its antihypertensive action via al-adrenoceptor blockage and Ca 2+ antagonism in vascular smooth muscle. Since the chemically similar 1 -(1-naphthyl) piperazine is known to be a 5-hydroxytryptamine2 receptor antagonist, the 5-hydroxytryptamine (5-HT) antagonistic properties of naft