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Inhibition of 25-hydroxyvitamin D 1α-hydroxylase by renal mitochondrial protein kinase-catalyzed phosphorylation

✍ Scribed by Jacob G. Ghazarian; Diane M. Yanda

Book ID: 115759195
Publisher: Elsevier Science
Year: 1985
Tongue: English
Weight: 760 KB
Volume: 132
Category: Article
ISSN: 0006-291X
DOI: 10.1016/0006-291x(85)91919-9

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## Abstract 1α,25‐Dihydroxyvitamin D~3~ [1α,25(OH)~2~D~3~], the hormonally active form of vitamin D~3~, has been shown to be a potent negative growth regulator of breast cancer cells both in vitro and in vivo. 1α,25(OH)~2~D~3~ acts through two different mechanisms. In addition to regulating gene tr