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Inhibition by verapamil of ionophore-mediated calcium translocation

โœ Scribed by W. J. Malaisse; G. Devis; G. Somers


Book ID
112657927
Publisher
Springer
Year
1977
Tongue
English
Weight
226 KB
Volume
33
Category
Article
ISSN
1420-682X

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โœ Deborah J. Cameron; Dr. James A. Majeski ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 447 KB

Peripheral blood monocyte-derived macrophages and polymorphonuclear leukocytes (PMNs) obtained from normal donors kill tumor cells in vitro. However, if verapamil is added to the macrophages or neutrophil tumor cell suspensions in microgram concentrations (0.1 pg to 0.1 mg), there is marked inhibiti