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Inhibition by troglitazone of the antigen-induced production of leukotrienes in immunoglobulin E-sensitized RBL-2H3 cells

✍ Scribed by Masamichi Yamashita; Mikie Kushihara; Noriyasu Hirasawa; Wataru Takasaki; Hidekuni Takahagi; Motoaki Takayanagi; Kazuo Ohuchi


Book ID
110004751
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
175 KB
Volume
129
Category
Article
ISSN
0007-1188

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✍ Russell I. Ludowyke; Krystina Warton; Lyndee L. Scurr πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 English βš– 889 KB

The role of serine/threonine protein phosphatases PP1 and PP2A in mast cell secretion was investigated using the phosphatase inhibitors okadaic acid and calyculin A. Calyculin A (5-25 n) inhibited antigen-induced secretion from a rat mucosal mast cell line (RBL-2H3) when added in conjunction with t