Inhibition by sulphydril blocking agents of the guinea-pig gut reaction to anaphylaxis and to anaphylotoxin

Conversion of Hageman factor (Factor XII

Conversion of Hageman factor (Factor XII) of the guinea pig to prekallikrein activator and inhibition of the formed kallikrein by a natural plasma inhibitor

✍ Y. Takeuchi; H. Z. Movat 📂 Article 📅 1972 🏛 John Wiley and Sons 🌐 English ⚖ 558 KB

## Abstract Aluminum hydroxide adsorbed guinea pig plasma was fractionated by QAE Sephadex A‐50. Fractions correcting the clotting defect in Factor XII‐deficient plasma (without having an effect on Factor XI‐deficient plasma) were pooled and rechromatographed twice through Sephadex G‐200. By gel fi