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Inhibition by mefloquine of Ca2+ stimulated phospholipid dependent protein kinase from rat spleen

โœ Scribed by Agarwal, Abha; Walter, Rolf D.

Book ID
122387888
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
244 KB
Volume
19
Category
Article
ISSN
0306-3623

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Gangliosides inhibit the phosphorylation of both small and large rat myelin basic proteins (SMBP, LMBP) by an endogenous phospholipid-sensitive Ca\*+-dependent protein kinase (C-kinase). Using a rat brain myelin preparation in an in vitro phosphorylation assay system, we determined the inhibition co