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Inhibition by glucocorticoids of the interleukin-1β-enhanced expression of the mast cell growth factor SCF

✍ Scribed by Carla Alexandra Da Silva; Olivier Kassel; Eric Mathieu; Gilbert Massard; Bernard Gasser; Nelly Frossard


Book ID
110007205
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
194 KB
Volume
135
Category
Article
ISSN
0007-1188

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## Abstract Connective tissue growth factor (CTGF/CCN2) is a matricellular protein induced by transforming growth factor (TGF)‐β and intimately involved with tissue repair and overexpressed in various fibrotic conditions. We previously showed that keratinocytes in vitro downregulate TGF‐β‐induced e