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Inhibition by dehydroepiandrosterone of growth and progression of persistent liver nodules in experimental rat liver carcinogenesis

✍ Scribed by M. Simile; R. M. Pascale; M. R. De Miglio; A. Nufris; L. Daino; M. A. Seddaiu; M. R. Muroni; K. N. Rao; F. Feo

Publisher: John Wiley and Sons
Year: 1995
Tongue: French
Weight: 790 KB
Volume: 62
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.2910620217

No coin nor oath required. For personal study only.

✦ Synopsis

Dehydroepiandrosterone (DHEA) inhibits the development of early pre-neoplastic lesions and prevents tumor development in various tissues when given to animals during the initiation/ promotion stages of carcinogenesis. Our purpose was to evaluate whether DHEA can also arrest the growth and progression of late lesions, such as persistent nodules (PNs) of rat liver. Male

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