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Inhibition by basic drugs of digoxin secretion into human bile

✍ Scribed by A. Hedman


Publisher
Springer
Year
1992
Tongue
English
Weight
301 KB
Volume
42
Category
Article
ISSN
0031-6970

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✦ Synopsis


Bile samples from previous interaction studies in man were re-analysed by a combined HPLC/radioimmunoassay method. Quinidine, quinine and verapamil but not probenecid or spironolactone were found to inhibit the biliary secretion of unchanged digoxin.