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Inhibition by auranofin of the production of prostaglandin E2 and nitric oxide in rat peritoneal macrophages

✍ Scribed by Masamichi Yamashita; Gaku Ichinowatari; Kouya Yamaki; Kazuo Ohuchi

Book ID
114017022
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
376 KB
Volume
368
Category
Article
ISSN
0014-2999

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Kupffer cells and other macrophages play an important role in pathogenesis of toxicants in the liver. The aim of this study was to evaluate the effect of macrophages on hepatocyte production of nitric oxide (NO), which has been previously reported to be protective toward oxidative stress induced in