Inhibition by acyclovir of cell growth and DNA synthesis of cells biochemically transformed with Herpesvirus genetic information
โ Scribed by Phillip A. Furman; Paul V. McGuirt; Paul M. Keller; James A. Fyfe; Gertrude B. Elion
- Book ID
- 119010061
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- English
- Weight
- 923 KB
- Volume
- 102
- Category
- Article
- ISSN
- 0042-6822
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Rat embryo fibroblasts (REF) morphologically transformed by herpes simplex virus type 2 (HSVโ2) and tumorโderived cells were tested for ability to grow in the presence of 9โ(2โhydroxyethoxymethyl) guanine (acyclovir). Results indicated that the effective dose of acyclovir (ACV) required
## Abstract Insulinโlike growth factor binding proteinโ3 (IGFBPโ3) has been proposed to mediate the growth inhibitory effects of transforming growth factor (TGF)โฮฒ in breast and prostate cancer cells. Both TGFโฮฒ and exogenous IGFBPโ3 inhibit DNA synthesis in Mv1 mink lung epithelial cells (CCL64).