A rationale for monoamine oxidase inhibi
β
Prof. C. W. Olanow
π
Article
π
1993
π
John Wiley and Sons
π
English
β 719 KB
Neurons in the substantia nigra may be vulnerable to oxidant stress because (a) the metabolism of dopamine generates peroxides. which, in the presence of iron. can lead to the formation of the highly reactive hydroxyl free radical; and (b) neuromelanin within nigral neurons can bind metals such as i