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Inhibition and down-regulation of gene transcription and guanylyl cyclase activity of NPRA by angiotensin II involving protein kinase C

✍ Scribed by Kiran K. Arise; Kailash N. Pandey


Book ID
116293475
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
284 KB
Volume
349
Category
Article
ISSN
0006-291X

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## Abstract All‐trans retinoic acid (ATRA), a synthetic derivative of vitamin A, inhibits the growth of breast cancer cells. To elucidate the mechanism by which ATRA causes cell growth inhibition, we examined changes in cell cycle and intracellular signaling pathways, focusing on protein kinase C (