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Inhibiting signal transducer and activator of transcription 3: rationality and rationale design of inhibitors

✍ Scribed by Mankan, Arun K; Greten, Florian R

Book ID: 115452445
Publisher: Informa plc
Year: 2011
Tongue: English
Weight: 465 KB
Volume: 20
Category: Article
ISSN: 1354-3784
DOI: 10.1517/13543784.2011.601739

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## Abstract Signal transducer and activator of transcription 3 (Stat3) is one of a family of cytoplasmic proteins that participate in normal cellular responses to cytokines and growth factors as transcription factors. Stat3 modulates various physiological functions including cell survival, cell‐cyc