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Inhibiting effects of nicotinamide on urethane-induced malformations and tumors in mice

โœ Scribed by H. Gotoh; T. Nomura; H. Nakajima; C. Hasegawa; Y. Sakamoto


Book ID
113251715
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
843 KB
Volume
199
Category
Article
ISSN
0165-1161

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A major goal in pre-clinical cancer chemoprevention research is to assess the predictive value of intermediate biomarker modulation towards tumor prevention. With this aim, BALB/c mice were treated with 10 daily i.p. injections of urethane (ethyl carbamate), each of 400 mg/kg body weight. Groups of