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Inherited protein-C deficiency, factor V G 1691 A and FV A 4070 G mutations in a child with internal cerebral venous thrombosis

✍ Scribed by T. Sipahi; Ç. Üner; Y. T. Yıldız; N. Akar

Book ID
105943176
Publisher
Springer-Verlag
Year
2000
Tongue
English
Weight
360 KB
Volume
30
Category
Article
ISSN
0301-0449

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✍ Lobna Bouaziz-Borgi; Philipe Nguyen; Nathalie Hezard; Umayya Musharrafieh; Wassi 📂 Article 📅 2007 🏛 Elsevier Science 🌐 English ⚖ 134 KB

Activated protein C resistance (APCR) is a significant risk factor for venous thromboembolism (VTE), with the factor V (FV) G1691A (Leiden) mutation accounting for the majority of inherited APCR cases. An additional FV polymorphism, A4074G (FV-HR2), reportedly increased VTE risk by some, but not all